SPECT Imaging and Psychiatry

This TED talk by Dr. Daniel Amen makes a good point. Why are psychiatrists the only doctors who don’t use any form of imaging in making their diagnoses? Dr. Amen discuses a newer form of brain scans that can help psychiatrists treat patients better and more effectively. 

Key points:

  • Psychiatrists are the only doctors who “guess” rather than look
  • SPECT can visually represent what is going on in the brain
  • Behavior is an outflow of a condition, not a condition in itself
  • Throwing medication at a problem can cause harm if given in incorrect diagnosis
  • We are not stuck with the brain we have, we can improve it on a “brain-smart” program 

Here is a SPECT image of Alzheimer’s Disease:

Image Credit: 2014 © Cedars-Sinai. All Rights Reserved. A 501(c)(3) non-profit organization

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MSG Effects on Hypothalamus Tissue and Weight Gain in Rats

I came across this image in an article published by Dr. Olney. This is an image of hypothalamus tissue exposed to MSG over time. The white tissue is necrotic.

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Dr. Olney also did research on the effects of MSG on weight gain. Below are two rats from the same litter. The left rat was given MSG and the right rat is the largest rat from the litter given no MSG (serving as experimental control).

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Here is a link to the actual article published in 1991:
Olney (1991)

Excitotoxins: MSG and Dr. Blaylock

I cam across a video by The Health Ranger on YouTube in which he inerviews Dr. Russell Blaylock a Neurosurgoun and the formost authority on excitotoxins in the brain. Here is the video:

Two books are referenced in the video they are:

In Bad Taste: The MSG Syndrome by Dr. George Schwartz

http://www.amazon.com/In-Bad-Taste-Syndrome-Signet/dp/0451165144/ref=sr_1_1?ie=UTF8&qid=1376180199&sr=8-1&keywords=in+bad+taste

and Dr. Blaylock’s first book Excitotoxins: The Taste That Kills

http://www.amazon.com/Excitotoxins-The-Taste-That-Kills/dp/0929173252/ref=sr_1_1?ie=UTF8&qid=1376180278&sr=8-1&keywords=excitotoxins

A couple highlights from the video:

  • MSG first appeared in foods in 1945 and the amount in food has doubled every decade thereafter.
  • Of all of the animals on earth, humans are the most susceptible to MSG toxicity.
  • MSG toxicity (MSG Syndrome) symptoms include: flushing of the face, heart palpitations, GI discomfort and diarrhea, damage to the brain over time that could lead to Alzheimer and Parkinson.
  • MSG can also be labeled as “Yeast Extract” on food labels.
  • Certain foods have naturally occurring MSG. This MSG is bonded, though, to a protein which takes time to break down and allow your body to process the MSG.
  • If you are active, MSG you eat can go to your muscles, if you are sedentary it will go to your brain.
  • Magnesium Pyruvate, Vitamin E and Vitamin C can protect the body from MSG toxicity.

Dr. Russell Blaylock’s website is:

http://russellblaylockmd.com/

A side note: the worlds primary producer of MSG is the Ajinomoto Company

http://www.ajinomoto-usa.com/

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Theanine, Lavander, and GABA

A while back I wrote a post about MSG and its connection to OCD.

After doing more research on natural anxiety supplements I came across L-Theanine. Theanine is able to easily pass through the bodies blood-brain-barrier and increase the levels of GABA (gamma-Aminobutyric acid) promoting relaxation.

An interesting illustration of GABA and its role within a synapse is shown in this illustration form Wikimedia Commons:

A similar increase in GABA was shown in patients who inhaled lavender essential oil. I am working on getting a reliable citation for the connection.

Most of my research is done at work during the rare slow times (I work as a pharmacy technician).

If you have any information about Theanine, Lavendar, GABA, OCD, or Anxiety, please post your information and/or links in the comments section.

 

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MSG (Monosodium Glutamate) and OCD

I noticed about a year and a half ago that I had a real problem with MSG. I don’t eat sushi very often but I remember one particular time I decided to load up on soy sauce. Later that day I had a pounding headache, the worst upset stomach, and it was difficult to breath. 

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I did some research on MSG and found that people who have OCD also have a small increase in the neurotransmitter “Glutamate”. (Read this article for a study done with OCD patients: http://img2.tapuz.co.il/forums/1_143264754.pdf )

I’ll have to find the citation but I remember another study talking about the role of Glutamate and the frontal lobe (see my first post).

Anyone else have similar problems with MSG? (Or MSG and OCD?)

Here is a picture of the structure of the neurotransmitter Glutamate:

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The Left Anterior Orbitofrontal Cortex

My first year of undergraduate education I was shocked when my professor told me that the disorders listed in the Diagnostic and Statistical Manual for Mental Disorders were disorders we knew how to treat, but didn’t know the causes.
I want to focus my work not just on treatments but causes.
On that note I have been reading about the Left Anterior Orbitofrontal Cortex. An area of the brain believed to play a role in causing Obsessive Compulsive Disorder.
I don’t have a lot of information to share as of right now but I plan on continuing my research in this area.
If you have any information about this specific region (or even areas of the frontal lobe in general) please feel free to share!

For more information on this region regarding its role in “secondary reinforcers” see this wordpress blog I found:
Secondary Reinforcers

I don’t want the knowledge I have received from even the small amount of education I have currently received to go to waste. It’s time to start looking for causes so we can start working on prevention.

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